AG2PI Field Day #8 - June 16, 2021
Functional Annotation of ANimal Genomes (FAANG)
June 16, 2021
10:30 AM - 12:00 PM
(US Central Time)
Purpose
An introduction to the global animal genomics consortium Functional Annotation of ANimal Genomes and example of how a successful working group can be created and utilized.
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Members of Functional Annotation of ANimal Genomes (FAANG) will introduce this global animal genomics consortium. They will share its goals and aspirations to provide resources for understanding the genome of all livestock and aquaculture species. The speakers will discuss how the consortium was envisioned, the foundations that were laid, its current activities and future plans, providing an example of a successful consortium in the agricultural genomics space. Visit the AG2PI website for full titles and summaries for each talk.
Field Day Speakers & Abstracts
The Functional Annotation of ANimal Genome initiative: boosting genotype-to-phenotype research in farmed animals.
The FAANG Consortium was developed at the grass-roots level by scientists who identified a need to annotate livestock and aquaculture species genomes. This talk will describe how the Consortium was created and resources developed through interactions with stakeholders and funding agencies. Current activities, especially those funded by European Commission H2020 will be summarized, and a future vision for FAANG will be outlined, with an emphasis on FAANG as a example for consortia development in the genomics arena.
Importance of rich FAIR
validated metadata, standardised protocols and analyses, and
open-access datasets for genotype to phenotype research.
A hallmark of successful genetics/genomics consortia is a strong emphasis on data collection, description and storage that allows efficient and effective data sharing among the community members. FAANG has been a leader in emphasizing a strong and well-organized set of metadata standards and protocols from the beginning, and this talk will describe the components of this community resource developed at EMBL-EBI. The principles underlying this infrastructure are continuing to be developed through collaboration with three 2020-funded EuroFAANG projects (AQUA-FAANG, BovReg and GENE-SWitCH). EMBL-EBI recently appointed two new team leaders (Peter Harrison and Sarah Dyer) to collaboratively develop data resources supporting scientists using genomics to improve crop and animal agriculture, enhancing resources centred around the world-renowned Ensembl genome browser (https://www.ensembl.org/).
Computational resources for understanding genomes to phenomes: FAANGMine and Future Cyberinfrastructure
Integrative yet easy-to-use resources for individual scientists to fully engage with genomics and genetics data are crucial. These resources include both web applications to visualize relationships among datasets as well as access to pre-computed summaries and genome annotations derived from raw data. This talk will describe development of such resources for the FAANG community, as well as efforts to further develop the cyberinfrastructure to house and utilize the expected deluge of data from animal genomics projects.
